The officials and researchers worried about interference from Iran after Iranians posing as members of the far-right Proud Boys group threatened Democrats not to vote. The Justice Department on Wednesday announced a takedown of dozens of Iranian propaganda sites targeting Americans. And Microsoft and United States Cyber Command separately took aim at Russian cybercriminals’ hacking infrastructure in an effort to stave off the kinds of ransomware attacks that could freeze up election systems.But on Tuesday, they breathed a sigh of relief as Election Day passed relatively unscathed. It was, one administration official said, just another Tuesday on the internet.Yet 24 hours later, it appeared Facebook and Twitter might have overlooked the deluge of disinformation targeting Spanish-speaking Americans. Spanish-language accounts with huge followings falsely said that Mr. Trump had secured an early victory, that social media was censoring his win and that Mr. Biden was cheating.- Advertisement – Twitter accounts with large followings pushed a debunked conspiracy theory, adopted by some prominent American conservatives, that election workers in Maricopa County, Ariz., had given Trump voters pens that could not be detected by ballot scanners. Others claimed that armed protesters funded by the billionaire Mr. Soros were taking over the U.S. Capitol. For weeks, officials and election security experts braced for what was widely expected to be an election marred by hacking and misinformation. They zeroed in on familiar adversaries in Russia, which weeks earlier had been caught hiring people in Mexico and Venezuela to push out Instagram and Facebook content.- Advertisement – MIAMI — The posts proliferated on election night before anything remotely definitive was known about the results of the presidential race. “Robado,” they falsely repeated again and again in Spanish: President Trump was being robbed of a victory. He had won Arizona. George Soros was funding violent “antifa riots.”The baseless social media messages to Latinos trying to delegitimize the election and the results for Joseph R. Biden Jr. circulated online on Tuesday night and into Wednesday, part of a disinformation campaign to undermine Latino confidence in the vote as it unfolded.- Advertisement – On the Spanish-language YouTube channel Campechaneando, a host warned viewers not to believe news that Mr. Biden had overtaken Mr. Trump in the Electoral College count. Some 160,000 people had watched the video by Wednesday. Ahead of Election Day, false news in Spanish tried to turn Latinos against Black Lives Matter and tie Mr. Biden to socialism, tactics that experts said could depress the Hispanic vote. Now that voting is complete, the rampant falsehoods have only garnered larger audiences — including among immigrants less familiar with the institutions of American democracy. The gist of the falsehoods is that the election is “rigged” against Mr. Trump.“These misinformation narratives are helping plunge the country further into chaos and confusion,” said Fadi Quran, a director at Avaaz, a nonprofit that tracks disinformation. He called the disinformation campaigns a “democratic emergency.” “The most vulnerable communities in the country are paying the highest price,” he said. By Wednesday, disinformation experts like Mr. Quran likened the flood of Spanish-language disinformation to an emergency and called on social media platforms to retroactively inform anyone who engaged with the content that the claims were false.The reach of the disinformation is vast. In just 24 hours, Spanish-language disinformation was generating traffic that eclipsed even the interference campaign by the Kremlin-backed Russian Internet Research Agency four years ago.On Facebook, a video posted to a seven-month-old Colombian account called Mr. Capacho en Vivo, with 40,000 followers, accused Twitter of censoring Mr. Trump’s victory and had already been viewed more than 500,000 times — far more traffic than Russian trolls generated with fake Black Lives Matter ads ahead of the 2016 election.Marketed as a global finance and political news page, the Colombian account pushed QAnon conspiracies, such as the baseless belief that leading Democrats are part of a global cabal of Satanist child molesters. On Monday, the same account posted an edited, misleading video of Mr. Biden touching children, falsely claiming that he was a “superpredator.” By Wednesday, the video had been watched about 45,000 times.Another Spanish-language influencer, Ciro Gómez Leyva, who has more than two million YouTube subscribers, posted a video late Tuesday in which he claimed that 150 members of antifa were descending on Washington with “gas masks, arms and shields.” While protesters did march outside the White House, there was no evidence that weapons were involved. On another Spanish-language channel, Informativo G24, with more than 500,000 subscribers, hosts compared Democrats to Nazis on Tuesday. The video was seen some 350,000 times.In Miami, a Spanish-language radio show, “Cada Tarde con Carinés Moncada y Agustín Acosta,” pushed debunked claims late Tuesday that Republican poll watchers had been barred from observing voting locations in Pennsylvania.In September, one of the show’s co-hosts, Carinés A. Moncada, had pushed a conspiracy theory that a co-founder of Black Lives Matter was involved in devil worship.It is difficult, if not impossible, to know how much false claims influenced Latino voters ahead of Election Day. But the hub of much of that misinformation was South Florida, home to a diverse community of Latinos, many of whom fled left-wing authoritarian regimes and are receptive to messaging about socialism.When the results from Miami-Dade County came in on Tuesday, Mr. Trump outperformed expectations. Robust support from Hispanic voters helped him win Florida easily and allowed Republicans to flip two congressional seats in the state.Juan Pablo Salas, a Colombian political analyst in Sarasota, Fla., said he worried that the misinformation involving Bogotá, Miami and Washington could be a coordinated effort between right-wing interests in Colombia and the U.S., “to essentially turn our Colombian-American community into the tip of the spear of the offense played by the extreme right.”“They’ve invested a lot of money in turning South Florida into a campaign bastion,” Mr. Salas said of the Republican Party and the party of former President Álvaro Uribe of Colombia, who is close with many Miami Republicans. On Tuesday night, Eduardo A. Gamarra, a professor of political science at Florida International University, agreed to analyze the election on NTN24, a television news network based in Colombia. He found himself on the air debating Omar Bula Escobar, a former United Nations representative notorious for, among other false claims, saying that Mr. Soros controls the Democratic Party, an anti-Semitic trope embraced by QAnon.Dr. Gamarra said he rejected Mr. Bula Escobar’s baseless claims of election fraud and then telephoned the network after the interview had concluded.“I said: ‘Don’t you ever do that to me again. Do background research on your guests,’” he said. “This is irresponsible.”A producer for the show did not immediately respond to a request for comment on Wednesday.Evelyn Pérez-Verdía, a Democratic Latino issues strategist in South Florida, said she spent four hours on Tuesday trying to debunk false claims on Spanish-language radio that Mr. Biden, a moderate, was a left-wing radical.“The Republicans called him a socialist, in those four hours, 20 times,” she said. “And a radical five times, and a Castro-Chavista” — a reference to Fidel Castro of Cuba and Hugo Chávez of Venezuela — “three times. Repeat a lie and repeat it until it becomes the truth.”Patricia Mazzei reported from Miami and Nicole Perlroth from San Francisco. – Advertisement –
– Advertisement – There’s still a very noticeable border running around the screen and Apple is sticking to a huge notch. Android companies that copied this years ago have surpassed Apple’s design with smaller notches and now even tinier front cameras embedded within screens. Of course none of them offer Apple’s secure Face ID hardware, but then again many people prefer a fingerprint sensor, which you don’t get here.On the rear, the dual camera module looks identical to that of the iPhone 11, but the hardware has been upgraded. You get the same 12-megapixel primary and ultra-wide cameras as on the iPhone 12 Pro, and both support Night Mode as well as Deep Fusion. Apple promises 27 percent better light gathering with the primary camera thanks to a f/1.6 aperture. 4K Dolby Vision HDR video recording also comes to this model which should make for some very crisp and vibrant clips.While more expensive than most people were hoping for, the iPhone 12 does deliver nearly all the features of the iPhone 12 Pro for two-thirds the starting price. You don’t get the flagship model’s higher amounts of storage, optical zoom camera, 60fps Dolby Vision video recording, LiDAR sensor, and stainless steel body, but those seem like things that are easy to live without considering the price difference.The 6.1-inch OLED display has the same specifications as that of the iPhone 12 Pro Each annual iPhone announcement is usually one of the most-hyped events of the year, even though there’s very little that’s actually revolutionary or even surprising about smartphones anymore. The iPhone 12 is one of four models announced by Apple this year, and is in many ways the least remarkable. It doesn’t have top-end flagship cameras or a brand-new LiDAR sensor like the iPhone 12 Pro and iPhone 12 Pro Max, and it doesn’t introduce a new size category that defies industry trends, which is where the iPhone 12 mini comes in.The plain, middle-of-the-road iPhone 12 is however set to be Apple’s bread-and-butter model for the next year, and could be extremely popular. Here are my first impressions.- Advertisement – First of all, the pricing. Storage options are 64GB, 128GB, and 256GB, and you’ll pay Rs. 79,900, Rs. 84,900, or Rs. 94,900 for them respectively. That’s quite a bit more than the iPhone 11 (Review) cost at launch time – Apple has moved the iPhone 12 up a tier, and you’ll have to settle for the smaller iPhone 12 mini if you were expecting the same prices. Launching soon, the iPhone 12 mini variants each cost Rs. 10,000 less for the same features and same amounts of storage.The iPhone 12 series introduces a significantly different (and heavily leaked) design style for the first time since the iPhone X. We now have a flat band running around the periphery of the phone rather than a curved frame. The corners are rounded but the front and back of the iPhone 12 meet its frame at 90 degree angles. There’s no curved-edge glass that flows into the metal and no chamfered or bevelled edges. It’s almost like the iPhone 5 generation, except even more minimalist.- Advertisement – You get the same Apple A14 Bionic SoC that the iPhone 12 Pro has, and also the same 6.1-inch 1170×2532-pixel OLED Super Retina XDR screen (but no 120Hz refresh rate), 12-megapixel front camera, IP68 rating, 17 hour claimed battery life, magnetic MagSafe wireless charging compatibility (though you’ll need to buy Apple’s own power adapter), and 5G (sub-6GHz) network support.Of course there are several highly capable Android devices that cost half as much and promise all the features you could possibly want. The Apple advantage will come down to iOS 14 integration, cameras, overall usability, and of course flaunt value.Do stay tuned to Gadgets 360 for a detailed review, coming up soon, in which we’ll dive into the iPhone 12’s features, build quality, software, performance, cameras, battery life, and much more. The iPhone 12 weighs 162g and is 74mm thick The look is pretty stark, and frankly even though it isn’t a huge change, the iPhone line did need a bit of freshness, and this serves the purpose. The sides don’t bulge outwards, which helps reduce bulk. The iPhone 12 is noticeably smaller in every dimension than the iPhone 11 and iPhone XR (Review), and also quite a lot lighter. It weighs 162g and is 7.4mm thick, compared to 194g and 8.3mm.If you’re worried that the flat sides make the iPhone 12 uncomfortable to hold, think again. The shape is a bit less organic, but the reduced bulk makes up for that. Owners of older iPhones will remember that corners like this are very easy to dent if the phone is dropped. Apple does promise reinforced glass on the rear and its new toughened Ceramic Shield material on the front, but you’re definitely going to want to buy a case. It also looks as though the edges of the aluminium frame could get chipped and scuffed over time.– Advertisement –
Jonny Evans is expected to return for Leicester after recovering from a back problem.The defender has missed the last three games but is in full training ahead of Sunday’s visit of Wolves, live on Sky Sports.Jamie Vardy will return after being rested for the 4-0 Europa League win over Braga but Ricardo Pereira (knee), Caglar Soyuncu (groin), Wilfred Ndidi (groin), Timothy Castagne (hamstring) and Daniel Amartey (hamstring) remain out. The 22-year-old winger made his debut in October’s win against Wales last month but was overlooked this time after the return of Raheem Sterling pushed him down a pecking order, which already includes Jadon Sancho and Jack Grealish.Barnes scored his second Premier League goal of the campaign in the 4-1 win at Leeds on Monday to propel the Foxes to second in the table and Rodgers is adamant he can bring something different to England. “Harvey is getting better and I’m sure there will be other squads for him to be involved in,” Rodgers said.“He is a player the national team don’t have, in that he is so direct with his running.“He started the season very well and earned the opportunity. Having met with the group last time it’ll prove a great motivation for him.“He was very grateful for the opportunity, he deserved it and has continued to play well.“All he can do is his job which is perform well for Leicester, he will continue to develop and improve.” 2:50 James Maddison also missed out on the England squad despite his recovery from the hip surgery which forced him to miss the end of last season.The midfielder, who has one cap, has started four of the Foxes’ last five games and scored three goals this season during the club’s impressive start to the season both domestically and in the Europa League.Leicester vs Wolves preview: Evans back for Foxes Sunday 8th November 1:00pm FREE TO WATCH: Highlights from Leicester’s win over Leeds in the Premier League. – Advertisement – – Advertisement – Image:James Maddison scored for Leicester against Braga in the Europa League on Thursday Kick off 2:00pm Leicester City manager Brendan Rodgers believes Harvey Barnes will earn an England recall after being left out of the latest squad.Barnes was omitted from Gareth Southgate’s squad to face the Republic of Ireland in a friendly and UEFA Nations League matches against Belgium and Iceland this month.- Advertisement – – Advertisement –
Parler’s recent growth has been so staggering that thousands of users have complained about how difficult it was to sign up because of the logjam of people creating new accounts. Mr. Matze said in a letter to Parler’s community on Tuesday that the influx “strained our networks’ capacity and caused some glitches and delays,” but the site was fixing the problems. To Mr. Adam, the social media companies appeared to be singling out conservative voices. So he decided to shift to Parler, a social networking app that he has used on and off for a year, and to largely ignore those two big platforms, he said.“Facebook started muting, deleting and labeling every conservative political post in my feed,” Mr. Adam said. “If you’re going to do something, you have to be fair to both sides. You don’t just get to pick one side to promote.” While social media sites marketed at conservatives have existed for years, they have often struggled to catch on more widely. Their invigoration now may add to a fracturing of the information ecosystem.“There are real dangers around a fractured misinformation system, especially as it relates to organizing against our electoral integrity,” said Shannon McGregor, a professor at the University of North Carolina, Chapel Hill, and senior researcher at the Center for Information, Technology, and Public Life.But Ms. McGregor said she was skeptical that any migration would lead to permanent departures from Facebook and Twitter. “If there is no one to argue with, no omnipresent journalists or media entities to react to, how long will it last?” she said.Facebook and Twitter declined to comment. The companies have denied censoring conservatives and typically point to their terms of service when an account breaks the rules. And while many conservatives are upset about their content being labeled or hidden, they are less willing to acknowledge that their posts can often clash with Facebook’s guidelines around disinformation and harmful content.Next week, Twitter’s chief executive, Jack Dorsey, and Facebook’s chief executive, Mark Zuckerberg, are scheduled to testify at a congressional hearing over their sites’ treatment of an unsubstantiated New York Post article that was critical of Hunter Biden, the son of President-elect Joseph R. Biden Jr. The hearing was called by Republicans who were incensed that the sites initially limited the distribution of the article. Last week after the polls closed, Facebook and Twitter began using many of those measures. When Mr. Trump posted that the election was being stolen from him, the companies labeled his messages. Facebook on Thursday also took down a rapidly growing Facebook group, Stop the Steal, which promoted the idea of a stolen election. Among those who have spoken out are Mark Levin, a far-right radio host with millions of listeners, who vented on his show last week that the tech and media companies were not representing the conservative point of view. Maria Bartiromo, a Fox News anchor, also expressed frustration with Twitter and said it was blocking conservatives’ statements.But Mr. Levin, Ms. Bartiromo and others did not stop there. They directed their followers to other social media apps and news sites that have positioned themselves as alternatives to Facebook and Twitter. The beneficiaries are Parler, a Twitter-like app that describes itself as the world’s “premier free speech social network,” the right-wing media app Newsmax, and other social sites like MeWe and Rumble, which have purposely welcomed conservatives. Over the weekend, Parler shot to the top of Apple’s App Store in downloads. As of Monday, it had eight million members, nearly double the 4.5 million it had last week. Rumble said it projected 75 million to 90 million people will watch a video on its site this month, up from 60.5 million last month. And Newsmax said more than 3 million people watched its election night coverage and that its app has recently been in the top-10 daily apps downloaded from Apple’s App Store. – Advertisement – Mr. Adam was one of millions of people who have migrated away from Facebook and Twitter since the election. As the companies have clamped down on misinformation, they have clashed with Republicans and conservatives who have spread lies about the election’s outcome, leading to claims that the tech platforms are censoring them. Melissa Zepeda, 32, a Republican and a registered nurse in northern Mississippi, said she and several of her co-workers recently switched to Newsmax from Fox News after it showed “favoritism to Biden.” Newsmax has not called the election in favor of Mr. Biden, one of the few news outlets not to do so.“So far, I like that they are non-biased, and cover a variety of information, not just the election,” Ms. Zepeda said.Mr. Ruddy, Newsmax’s chief executive and a confidant of Mr. Trump’s, said viewership and social media interactions with his site have soared. The surge came partly from conservatives who were searching for a place where their opinions are represented, he said. He added that it was important for publishers to have ideological diversity. – Advertisement – – Advertisement – “Parler is a breath of fresh air for those weary and wary of the way they’ve been treated by our competitors,” Jeffrey Wernick, Parler’s chief operating officer, said in a statement. “Our growth is not attributable to any one person or group, but rather to Parler’s efforts to earn our community’s trust.” Mr. Pavlovski added that Rumble prohibits explicit content, terrorist propaganda and harassment. But he said it was largely not in the business of sorting out misinformation or curbing speech.“I don’t want to pretend to sit here and know what the truth is or have the capabilities to know how to do that,” he said. On other platforms, he added, “people are not allowed to have debate anymore.”Many people have also sought out further-right news publications. That has been a boon for Newsmax, a right-wing news website and television channel founded in 1998 by the conservative journalist Christopher Ruddy. Last week, Newsmax gained steam after Fox News called the swing state of Arizona in favor of Mr. Biden, incensing Mr. Trump’s base. (The New York Times has not called Arizona in favor of either candidate.) Corey Adam, a political comedian from Minneapolis, joined a mass social media switcheroo last week.That was when Mr. Adam, 39, a conservative and libertarian, watched Twitter and Facebook add labels to social media posts from President Trump and other Republicans who falsely claimed he had won the election. Many of the labels said the assertions were disputed. And on Twitter, some of Mr. Trump’s tweets were hidden completely.- Advertisement – “There’s a liberal echo chamber that’s pretty damn big,” he said. “Conservatives just have less options, but if they seek them out, they’re there.”It might be too early to know whether a widespread, permanent shift away from major outlets will last, especially given the reach of Facebook, Twitter and Fox News. While conservative threats of mass migration away from mainstream apps and news have occurred periodically, people still seem to return to the biggest platforms.Ms. Zepeda, a longtime Facebook user, said she would keep her Facebook account to maintain access to the pictures she’s uploaded over the years. But she expects to drop the social network as a daily destination, joining one of the many Facebook groups that are planning a “Mass Exit off Facebook to Parler & MeWe,” scheduled for Friday.“I’m tired of the bias towards Democrats and liberals,” she said. Despite the conservative ire, Facebook and Twitter have long taken a mostly hands-off approach to digital speech. In recent months, however, the companies ramped up their efforts to prevent election misinformation. Facebook and Twitter said they would label false posts and slow down how quickly they could be shared, among other moves. They said many of the changes would be temporary. Some new Parler users said the site was an alternative to extreme platforms like Gab, another social media site that has been a haven for racist memes and content. Andrew Torba, founder and chief executive of Gab, said in an email, “Jesus is King, speak freely on Gab.com.” He also sent a link noting that Gab had seen record user growth over the last week.Others have gravitated to Rumble, a video site founded in 2013 that has emerged as a conservative YouTube. Rumble makes money in a variety of ways, including by running ads and selling its technology.Chris Pavlovski, Rumble’s founder and chief executive, said the site had been on a “rocket ship” of growth since the summer — and even more so since the election. Representative Devin Nunes, Republican of California, and Mr. Bongino are on Rumble and have seen their audiences expand rapidly on the site, he said. That moved people like Mr. Adam to switch to alternative apps like Parler, which is owned in part by the conservative media personality Dan Bongino. Founded in 2018 by two Nevada-based software engineers, John Matze and Jared Thomson, Parler — which is named after the French word meaning “to speak” — has said it is a free speech platform, with much looser guidelines around what people can post to the site.On Parler, users can see posts about MAGA fodder and QAnon, the pro-Trump conspiracy theory that asserts that some top Democrats are satanic pedophiles. Anti-Semitic theories abound. Donald Trump Jr., Senator Ted Cruz, Republican of Texas, and Rudolph W. Giuliani, President Trump’s personal lawyer, all have Parler accounts. Updated Nov. 11, 2020, 11:06 p.m. ET
Apart from the capacity, the teardown reveals that the iPhone 12 Pro Max battery comes in an L shape. This reminds us of the iPhone X that also included an L-shaped battery.The iPhone 12 Pro Max teardown also suggests that the logic board powering the new model is the same as that of the iPhone 12 and iPhone 12 Pro. There are also apparently some important components that are identical across all three models. These include the TrueDepth Camera system at the front that enables facial recognition as well as the A14 Bionic chip.– Advertisement – iPhone 12 Pro Max teardown video has been released on Weibo ahead of its global availability and gives us a glimpse of its internal components. Most importantly, it shows the battery capacity of the most premium model of the latest iPhone series. Apple is currently taking pre-orders for the iPhone 12 Pro Max, while its global availability will begin later today. Alongside the iPhone 12 Pro Max, the iPhone 12 mini is also coming to the global markets today. The two iPhone models will join the iPhone 12 and the iPhone 12 Pro that are already available in markets including India and the US.The over three-minute teardown video posted on Weibo shows that the iPhone 12 Pro Max includes a 3,687mAh battery. The battery capacity is identical to what was spotted on China’s TENAA earlier and is lower than the 3,969mAh battery available on the iPhone 11 Pro Max.- Advertisement – – Advertisement – iPhone 12 Pro Max teardown suggests the same logic board that’s available on iPhone 12Photo Credit: Weibo Apple has also offered a similar rear camera setup on both iPhone 12 Pro and iPhone 12 Pro Max. Although the camera performance of the iPhone 12 Pro Max is yet to be tested publicly, the teardown shows the presence of the LiDAR sensor that helps enhance depth sensing.- Advertisement – However, the latest teardown video doesn’t provide any details on the repairability of the iPhone 12 Pro Max. It is unclear whether key components of the new model are easily replaceable.Since the iPhone 12 Pro Max goes on sale today, you can expect some more detailed teardown videos hitting the Web soon. Those are likely to answer other important questions about the new model.Are iPhone 12 mini, HomePod mini the Perfect Apple Devices for India? We discussed this on Orbital, our weekly technology podcast, which you can subscribe to via Apple Podcasts, Google Podcasts, or RSS, download the episode, or just hit the play button below.
May 4, 2005 (CIDRAP News) – Vietnam is moving forward with a plan to fight the spread of avian influenza by vaccinating roughly 600,000 chickens in Ho Chi Minh City, according to news reports today.A vaccine produced by a French company called Merial will be administered to chickens on commercial farms this month, the Associated Press (AP) reported today, citing Phan Xuan Thao, deputy director of the city’s animal health department.Only chickens on commercial farms will receive the vaccine, Thao told the AP. They will be closely monitored. If results are good, the vaccine could be used more widely in Vietnam.Vietnam’s Tuoi Tre (Youth) newspaper quoted a national animal health department official as saying that Vietnam had agreed to let commercial chicken farms test another vaccine, the AP reported. That vaccine, produced in the Netherlands, could be used on up to 2.7 million chickens. The farms are run by Vietnam Breeding Co. and Japfa Comfeed Co., according to a report by Thanh Nien News in Vietnam.The reports did not specify how the vaccinations would be conducted, but an April 19 story by the Vietnam News Service said the government planned to try using an H5N2 vaccine in chickens and an H5N1 vaccine in waterfowl. The story said the vaccinations would begin in Tien Giang and Nam Dinh provinces in southern and northern Vietnam, respectively.Poultry immunization for avian flu has been controversial in Asian countries because of concerns that vaccinated birds could still carry the virus asymptomatically and that this could hurt food exports.
Mar 10, 2008 (CIDRAP News) – Animal health officials in India reported that H5N1 avian influenza has resurfaced in West Bengal state, as officials in Vietnam said the virus has struck poultry in another province as well as a farm near Hanoi.Anisur Rahaman, the state’s animal resources development minister, said nearly 1,000 birds have died of the H5N1 virus over the past 10 days in two villages near India’s border with Bangladesh, the Associated Press (AP) reported today. Veterinary workers started culling birds in the area after the H5N1 outbreak was confirmed, the report said.One of the affected districts is Murshidabad, an area that had reported earlier outbreaks, Reuters reported today. Bird deaths were also reported in Birbhum district, where the original outbreak started, the report said.The new outbreaks were reported less than 2 weeks after the United Nations Food and Agriculture Organization (FAO) praised India for its success in fighting its worst avian influenza outbreak. The initial round of outbreaks began in mid January in the village of Margram. The virus spread quickly, striking poultry in 13 of the state’s 19 districts and prompting the culling of almost 4 million birds.FAO officials had also said that the country was at high risk for more outbreaks and urged India to remain vigilant.Rahaman told the AP the new outbreaks could have resulted from villagers hiding their poultry during earlier culling operations, or the virus could have been transmitted through the smuggling of birds from Bangladesh, a country that is experiencing widespread H5N1 outbreaks.Elsewhere, animal health officials in Vietnam said the H5N1 virus struck birds in Quang Tri province in the central part of the country, a local newspaper, Pioneer, reported today, according to Xinhua, China’s state news agency. The outbreak killed 90 of 600 unvaccinated ducks at a household, and the remaining birds were culled, the report said.Vietnam’s agriculture ministry said the new outbreaks push the number of provinces reporting recent outbreaks to nine, Xinhua reported. Most are in the northern part of the country.On Mar 7, veterinary officials reported an H5N1 outbreak at a farm on the outskirts of Hanoi, the nation’s capital, Agence France-Presse reported that same day. The virus hit about 2,000 unvaccinated chicken, ducks, and geese, the report said. The remaining birds were culled, and birds in nearby communes were vaccinated.In other developments, agriculture officials in China today said it has received reports of 12 H5N1 outbreaks this year, Xinhua reported.Li Jinxiang, director of the ministry’s veterinary department, told Xinhua that three of the outbreaks have been confirmed, two in Tibet and one in Guizhou province, all in the southwestern part of the country.He said unusually cold and snowy conditions contributed to the outbreaks by creating a favorable environment for the virus, hampering regularly scheduled bird vaccination drives, and harming living conditions for livestock.Jinxiang said government departments across China are launching spring disease control and immunization efforts and that the ministry has gathered 5 billion milliliters of vaccines for immunization activities.
Given the plasma concentrations observed in this study, the authors predict that ST-246 doses ranging from 400 to 800 mg will provide nonfasting humans with protection comparable to that seen in a study in nonhuman primates that received a high dose of monkeypox virus. In the animal subjects, an ST-246 dose of 10 mg/kg provided full protection from death. Jordan R, Tien D, Bolken TC, et al. Single-dose safety and pharmacokinetics of ST-246, a novel orthopoxvirus egress inhibitor. Antimicrobial Agents Chemo 2008 May;52(5):1721-7 [Abstract] May 17, 2007, CIDRAP News story “CDC reports on soldier’s son who had severe vaccinia infection” The study was conducted by scientists from Siga Technolgoies Inc., Corvallis, Ore., developer of ST-246, and two other private companies, with Siga’s Robert Jordan as the lead author. ST-246 was used on an emergency basis last year in a 2-year-old boy who became critically ill with eczema vaccinatum, a form of vaccinia virus infection. The boy, who survived, was infected through exposure to his father, a soldier who had received a smallpox shot. Six of the 38 volunteers had an adverse event, such as neutropenia, constipation, back pain, or headache, but the incidence was higher in the placebo subjects (2 of 7, or 29%) than in the treated subjects (4 of 31, 13%). Some of the fasting volunteers had slight, transient decreases in white blood cell counts and neutrophil percentages 1 day after treatment, but this was seen in both the ST-246 and placebo groups. In the safety trial, the researchers recruited 40 healthy adult volunteers and divided them into four groups. In three of the groups, volunteers who were fasting received ST-246 in a single oral dose of 500, 1,000, or 2,000 mg, or a placebo. Volunteers in the fourth group received either 1,000 mg of ST-246 or a placebo after consuming a high-fat meal. In all, 31 volunteers received the drug and 7 received a placebo. May 8, 2008 (CIDRAP News) An antiviral drug being developed to provide protection against smallpox and related viruses performed well in the first test of its safety and activity in humans, according to a report in the May issue of Antimicrobial Agents and Chemotherapy. Measurable plasma concentrations of the drug were found in all the treated volunteers from a half-hour to as long as 72 hours after administration, the report says. It took an average of 2 to 3 hours after dosing for the drug to reach maximum concentration. Food seemed to increase the plasma presence of the drug, as the nonfasting volunteers had 1.6-fold higher maximum concentration than the fasting volunteers. ST-246 was identified in a screen of more than 350,000 compounds designed to find substances that could inhibit vaccinia virus, which is a close relative of smallpox virus and is used in smallpox vaccine. In preclinical studies, ST-246 protected mice from lethal infection with vaccinia virus, cowpox virus, and ectromelia virus, according to the new report. Also, in unpublished studies, the drug was active against monkeypox in squirrels and against both monkeypox and smallpox viruses in monkeys, the report says. “Administration of ST-246 resulted in exposure levels predicted to be sufficient for inhibiting orthopoxvirus replication compared to exposure levels in nonhuman primates in which ST-246 protected animals from lethal orthopoxvirus nfection,” the report states. The drug, called ST-246, was generally well tolerated and caused no serious adverse events in a study involving 38 volunteers, the report says. The doses used in the study produced plasma concentrations comparable to those that protected animals from infections of lethal orthopoxvirus (the family that includes smallpox) in preclinical experiments. See also: Currently, vaccination within the first 4 days after exposure is considered the only reliable treatment for smallpox, although the antiviral drug cidofovir has shown activity against orthopoxviruses. Smallpox disease was eradicated in the 1970s, but there is concern that secret stocks of the virus may still exist and fall into the hands of terrorists or rogue nations. (The only known stocks of the virus, kept for research, are held in government laboratories in the United States and Russia.) Mar 19, 2007, CIDRAP News story “Son of vaccinated soldier has severe vaccinia infection”
Jul 28, 2009Japan finds two more Tamiflu-resistant H1N1 casesJapan has detected two more cases of Tamiflu-resistant pandemic H1N1 flu, Alexander Klimov, PhD, of the CDC’s flu surveillance branch, revealed at the CDC’s vaccine advisory committee today. He also said that Chinese officials revealed during a World Health Organization conference call that they may have one more antiviral-resistant case. Klimov said all cases so far have been linked to Tamiflu prophylaxis or treatment, except for one involving an American girl who was diagnosed in Hong Kong.[Jul 29 ACIP meeting agenda] Latin America has lion’s share of H1N1 deathsAlthough novel H1N1 flu strain is spreading worldwide, Latin America, currently in its winter season, is being disproportionately hit right now, according to WA Today.com, an Australian news service. Of the 816 deaths the World Health Organization has so far confirmed, two thirds have occurred in Latin America, the report said.[Jul 29 WAtoday article] UK advises nurseries to remove soft toysBritain’s Department of Children, Schools and Families has come under fire for issuing recommendations that nurseries and “childminders” remove communal soft toys from care settings to help contain the spread of H1N1 flu, saying the toys cannot be cleaned adequately. The agency also recommend that crayons and pencils not be shared and large assemblies be suspended. Defenders of the guidance say it is sensible but should be administered sensitively so as not to upset children.[Jul 29 The Times article] Military may assist with US H1N1 responseUS military personnel may work alongside civilian authorities during any significant outbreaks of the H1N1 influenza virus this fall, according a CNN report. Unnamed Department of Defense officials said the proposal is awaiting approval by Secretary Robert Gates. Personnel from all branches of the military may be involved, and it has not been determined whether the troops would be pulled from active duty or from the National Guard and/or reserves.[Jul 29 CNN article] Canada to use adjuvanted H1N1 vaccineCanadian health officials anticipate using an adjuvant to address the possible need to stretch supplies of an H1N1 influenza vaccine this fall, according to a Canadian Press story. Neither Canada nor the United States have licensed flu vaccines with adjuvants before. Health Canada has worked with GlaxoSmithKline on safety studies of the AS03 adjuvant for H5N1 vaccine and is urging the company to do a small trial with an H1N1 vaccine. US officials have been more circumspect on the subject.[Jul 29 Canadian Press story]
Journalists Mirjana Žugec – Pavičić, Eduard Kišić, Željko Žutelija, Vesna Jurić Rukavina and Branko Uvodić are the winners of the FEST award – a prestigious international award given by the European Federation of Tourist Journalists (FEST) at the suggestion of the International Association of Tourist Journalists and Writers in Tourism (FIJET) . Žugec – Pavičić, Kišić and Žutelija are members of the HND Tourist Journalists’ Association.Mirjana Žugec – Pavičić, journalists and editors on the Second Program of Croatian Radio and Glas Hrvatske (HRT – HR), the award was presented for exceptional contribution to journalism, especially for radio expression in travel journalism, for professionalism and creativity. Eduard Kišić, journalist and editor of HRT Rijeka, was awarded for his exceptional contribution to Radio – TV journalism, tourist journalism and FIJET activities. Journalist and publicist Željko Žutelija received an award for special contribution to the high standards of Croatian journalism. Branko Uvodić, HRT’s editor and presenter was awarded for excellence in the overall presentation of the beauty and richness of Croatian traditional heritage and culture. Vesna Juric Rukavina, editor, publicist and journalist received an award for outstanding contribution to journalism, especially travel writing.The awards were given to them on November 10.11.2017, 2016. in Solin, during the International Festival of Tourism, Film, Landscape (INTERSTAS), the International Tourist Film Festival (ITF’CRO) and the Croatian Cities and Places Competition for the GOLDEN FLOWER OF EUROPE and Dr. “Lucija Čikeš” (KEA – CRO ‘XNUMX) .Congratulations to all nominated and awarded journalists and colleagues.